Arthrofibrosis after total knee arthroplasty: patients with keloids at risk

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A potential mode of action for Anakinra in patients with arthrofibrosis following total knee arthroplasty

Arthrofibrosis is a fibroproliferative disease characterised by excessive deposition of extracellular matrix components intra-articularly leading to pain and restricted range of movement. Although frequently observed following total knee arthroplasty (TKA) no therapeutic options exist. A pilot study demonstrated that intra-articular injection of Anakinra, an IL-1R antagonist, improved range of ...

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ژورنال

عنوان ژورنال: Journal of Orthopaedics and Traumatology

سال: 2021

ISSN: 1590-9921,1590-9999

DOI: 10.1186/s10195-020-00563-7